AMAZING SURPRISE and delicious cake from my awesome lab members for my xx(?!) birthday!!! THANK YOU all so much. I am so happy and honoured to be working with you!

A Regulatory Element in the Intrinsically Disordered C-Terminal Region of LMTK3 Modulates Its Kinase Domain Interactions and Breast Cancer Phenotypes In this study, we have identified a previously uncharacterised regulatory element within the LMTK3 C-terminus that can modulate its kinase domain interactions and LMTK3-driven oncogenic functions. Ultimately, by understanding and potentially blocking this switch, the study opens up a new avenue for developing therapies that coul

1. The “Hit-and-Run” legacy: epigenetic locking and the survival switch in H. pylori-associated gastric cancer This article introduces a novel "Survival Switch" hypothesis to explain the persistent risk of gastric cancer (GC) even after H. pylori eradication. The review's significance lies in shifting the clinical paradigm from simply eradicating the pathogen to a "Wake-up and Kill" strategy. This involves using epigenetic drugs to reverse the mesenchymal phenotype, thereby

Great and huge Chinese lunch with the team (+1)! I'd like to welcome our 2 new PhD students (Hanning and Yuxin), who will officially start their work in September! Looking forward to it! At the same time, I would like to say farewell to Niloufar, and wish her all the best as she embarks on a new PhD chapter abroad!! 🥳 You will always be welcomed in our lab!

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis New multi-national collaborative study analysing small extracellular vesicles (sEVs) from 206 plasma samples across three independent cohorts (UK, Denmark, NZ), and identifying 45 consistently altered proteins and 20 microRNAs in glioma patients. Our machine learning models achieved AUCs of 0.931-0.971, with 100% accuracy in an independent l

New review paper from our lab that highlights how tumor-derived extracellular vesicles (EVs) coordinate breast cancer lung metastasis by simultaneously inducing epithelial-mesenchymal transition (EMT) and establishing a pre-metastatic pulmonary niche. It proposes that distinct EV subpopulations act synergistically—not single multitasking vesicles—offering a new framework for EV-based therapeutic strategies. You can read the whole paper here: https://doi.org/10.1002/brv.70167

New paper from our lab implicating LMTK3 in breast cancer angiogenesis and mesenchymal-epithelial transition. You can read the whole paper here: https://www.nature.com/articles/s41417-026-01001-2

I am truly delighted and deeply honored to have been awarded the prestigious and highly competitive China’s Overseas High-Level (National) Talent Award! Since my arrival in China (August 2024), I have been fortunate to receive tremendous support from countless colleagues at ZCMU and the First Affiliated Hospital of Hangzhou. I extend my sincere gratitude for all they have done to welcome and assist me. 🙏 I also want to express how incredibly proud I am of my research group .

I am delighted to announce that I will be assuming the role of Editor-in-Chief of Oncogene ( https://www.nature.com/onc/ ) from 1st of January 2026. It is both an honor and a profound privilege to lead a journal with such a distinguished legacy, and I embrace this responsibility with great commitment. Looking ahead, I am committed to promoting cutting-edge, interdisciplinary cancer research and attract the highest quality submissions from leading laboratories worldwide by ens

I couldn’t be more proud of my dream lab team! Thank you all for being so great and for tolerating me!!!

I had the honour again to participate in this prestigious oncology symposium and present our work on identifying an ‘extracellular vesicles-liquid biopsy diagnostic biomarker signature for Glioblastoma'.

!!! Huge Congratulations to Dr. Jian Lu, Dr. Daniel de Vega Perez and Dr. Heng Liang for being succesful in their grant applications for the '2025 ZCMU - Talent Development Program' !!! That's 100% success rate for our postdocs! Keep up the great work.

I am very honoured to be invited to attend the ‘190th anniversary of Sun Yat-sen Memorial Hospital’ (Guangzhou) and to participate at the ‘Golden Bay Summit’ (Shanwei) for a second consecutive year. I was impressed about the pioneering work of this hospital related to western medicine practice, and I was delighted to learn more about this revolutionary leader (Sun Yat-sen) who was the forerunner of the democratic revolution in China 👍

Work hard, play harder! 👍💪 It is very clear that the GLARE members have plenty of great qualities and skills outside the lab too! Go team! I’m very proud of all of you 👍

I had the honour to be invited and present our work at this exciting event in Beijing. We have already established some exciting collaborations with colleagues (neurosurgeons) from Beijing Tiantan Hospital. I am amazed by their overall excitement and willingness to collaborate and do groundbreaking research 👏

New review paper from our lab discussing different CRISPR screening approaches used in breast cancer research. You can read the whole...

I was very happy to discuss with Angi Mariani from 'Latest TV' (Brighton, UK) about our recent discoveries and the overall progress of...

I am very honoured to have been invited to present our work at this great conference! A huge 'Thank you' to Professor Maria Roubelakis ...

‼️ HOT OFF THE PRESS‼️ I am delighted to share our lab's new paper published in Molecular Cancer! In this study, we describe a new role...