New paper published in 'Cells' (17/08/2026)

A Regulatory Element in the Intrinsically Disordered C-Terminal Region of LMTK3 Modulates Its Kinase Domain Interactions and Breast Cancer Phenotypes

In this study, we have identified a previously uncharacterised regulatory element within the LMTK3 C-terminus that can modulate its kinase domain interactions and LMTK3-driven oncogenic functions. Ultimately, by understanding and potentially blocking this switch, the study opens up a new avenue for developing therapies that could stop breast cancer from progressing.